High Content Screening; Plays A Significant Role in Infectious Disease Research and Drug Discovery

High Content Screening

High Content Screening, also known as high-content analysis, is widely used in drug discovery and biological research to identify substances such as RNAi, peptides, or small molecules that alter the phenotype of a cell in a desired manner. This technique is used for almost all stages involved in drug discovery. This includes selectivity, cell sorting, permeability, absorption, and metabolism. In high content screening, cells are first incubated with the substance and after a period of time, structures and molecular components of the cells are analyzed.

High Content Screening is a method used in many biochemistry studies and drug development to identify toxic materials that regulate the physiology of a particular cell in a targeted way. It is an approach to cell biology that combines automated imaging and quantitative data analysis in a high-throughput format suitable for large-scale applications such as drug discovery. This is why high content screening is important for pharmaceutical companies.

High Content Screening is a critical step in drug discovery. It aims to rapidly identify active compounds that modulate the particular target, pathway, or biochemical/cellular event. It is a drug discovery process that allows automated testing of the large numbers of chemical and/or biological compounds for a specific biological target. It is considered as an important tool in supporting drug discovery and development. The important tool for is the new drug delivery system that uses the protein complexes as delivery vehicles.

It is a process used routinely in early-stage drug discovery. It is multiplexed, functional cell-based screening. It can be used in all aspects of drug discovery as an engine for driving lead discovery. For instance, the Operetta system is designed to provide edge High Content Screening and analysis capabilities to drug discovery and cellular science research laboratories.



 

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